Kinetic studies of the metabolism of foreign organic compounds. IV. The conjugation of phenols with sulphuric acid.
نویسندگان
چکیده
completely converted oxaloacetic acid into pyruvic acid. In contrast, extraction of the plants with 2N-NaOH immediately inactivated the decarboxylase and stabilized the oxo acid levels, so that oxaloacetic acid could be reliably estimated. Although our plant extraction procedure involved slightly acid pH values this could not explain the apparent absence of oxaloacetic acid, since extractions using 2N-NaOH also failed to reveal the acid.
منابع مشابه
Kinetic studies of the metabolism of foreign organic compounds. III. The conjugation of phenols with glucuronic acid.
It is well known that phenols, whether formed in vivo or administered as such, are excreted by many species largely conjugated with glucuronic and sulphuric acids. The extent of the conjugation with glucuronic acid has been examined for many phenols and by many workers, the result usually being recorded as a percentage of the dose excreted as glucuronide in 24 or 48 hr. Several of the glucuroni...
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عنوان ژورنال:
- The Biochemical journal
دوره 61 1 شماره
صفحات -
تاریخ انتشار 1950